Hyaluronidase | Hyalase

Hyaluronidase was used to dissolve the very poorly injected dermal filler

This is a product which may be injected into the skin to dissolve the most common type of dermal fillers

Problems after dermal filler which can be treated with Hyaluronidase / Hyalase:

Lumps/ bumps of dermal filler: Hyalase / hyaluronidase can be injected to dissolve the lump of dermal filler product

Unevenness of dermal filler: Hylase /hyaluronidase can be injected to even out and smooth the appearance of dermal filler

Infections: With an infection related to dermal filler injection, hyalase /hylauronidase may be used.

Blue appearance under the skin due to dermal filler (Tyndall Effect): This will resolve with treatment with hyaluronidase / hyalase

Asymmetry of dermal filler: This can be treated with hyalase / hyaluronidase  being injected into the larger side to bring the size down to match the other side

Overtreatment with dermal filler: This can be treated with hyalase / hylauronidase.

Filler placed in the wrong area: This can be treated

Vascular events relating to dermal filler injection: If an artery / arteriole is blocked during a dermal filler treatment, causing blood supply to the skin to be compromised. Hyalase / hylauronidase should be injected immediately to attempt to prevent skin necrosis in the area

Procedure for injection of hyalase.

The patient will be assessed through history and examination and the treatment will be discussed. The risks side effects will be discussed.

Photos will be taken.

If it is possible to use a needle to remove dermal filler, then this option is preferable to hyalase / hyaluronidase treatment and this will be performed. Also with asymmetries, if the addition of product will give a better cosmetic result, then this will be discussed.

A test patch of an injection of hyalase / hyaluronidase into the skin of  the forearm arm may be used if the practitioner is concerned about allergy.

The skin will be cleaned.

Pressure will be applied to the area after injection with a gauze.

The patient will notice a reduction of the dermal filler within 1-2 days.

The patient should be reviewed at 1-4 weeks (all swelling must have resolved from the previous hyalase injection)

Risks of Hyalase / Hyaluronidase

Side effects are uncommon

Allergy. Can be very severe, including risk of anaphylaxis, which is very rare. Also risk of allergy in the local area of injection including redness and swelling.

Removing too much dermal filler The result of the dermal filler may be completely reversed, when only a reduction in the amount of dermal filler was planned

Removing the patients own  xxx (not allowed to say this due to TGA) This is a theoretic risk, but not one that is important in practice. When natural XXX is degraded it is reformed almost just as quickly. In fact, natural XXX is turned over on a daily basis so your body naturally degrades its own XXX and replaces it.

Infection: Always a possibility when introducing a needle into the skin

Common areas where hyaluronidase are used

The most common area for use of hyalase after dermal fillers is in the tear troughs, also the lips and cheeks and temples

Cost of Hyalase / Hylauronidase

See our pricing page for hyalase pricing.


NB Blue lump of dermal filler under right eye
Lump of dermal filler under eye 6 weeks after injection, needs treatment with hyalase
Lump of dermal filler under eye after injection, may require treatment with hyalase
Lump of dermal filler under right eye, 2 years after treatment of tear troughs, requires removal with hyalase
Lumps and blue appearance (Tyndall effect) due to poor injection technique to under eyes. For Hyalase hyaluronidase treatment
Patient presented with large lump in lip over 12 months after treatment with dermal filler. Hyaluronidase / hyalase may be required to dissolve lump