
Hyaluronidase (Hyalase) Information – The Manse Clinic Sydney
This is a prescription-only product that may be used by a qualified medical practitioner in certain situations to address complications related to previous cosmetic procedures.
Situations Where Hyaluronidase / Hyalase May Be Considered
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Lumps or bumps:
Hyalase / hyaluronidase may be used by a doctor to help dissolve localised irregularities. -
Unevenness of results:
In some cases, Hyalase / hyaluronidase may be used to smooth the appearance of treated areas. -
Infections:
When infection is associated with a previous cosmetic procedure, Hyalase / hyaluronidase may be part of a management plan as determined by the treating doctor. -
Blue appearance under the skin (Tyndall effect):
This may improve following medical treatment with Hyalase / hyaluronidase. -
Asymmetry:
Hyalase / hyaluronidase may be used to reduce product volume in one area to improve balance. -
Overtreatment:
Where excessive product is present, Hyalase / hyaluronidase can assist in reducing the amount. -
Vascular events:
In rare cases where blood flow is compromised after a cosmetic procedure, Hyalase / hyaluronidase may be administered promptly by a doctor as part of emergency management to help restore circulation and reduce the risk of tissue injury.
Procedure for Hyaluronidase / Hyalase Treatment
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The patient will be assessed through history and examination, and treatment options will be discussed.
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Risks and potential side effects will be reviewed.
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Photos may be taken for documentation.
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If appropriate, a needle aspiration of the area may be performed instead of Hyalase / hyaluronidase use.
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If allergy is a concern, a test patch on the forearm may be performed prior to treatment.
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The skin will be cleaned before the procedure.
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Pressure will be applied to the treated area with sterile gauze afterward.
Patients may notice improvement within 1–2 days.
A review appointment is recommended at 1–4 weeks, once any swelling has subsided.
Risks and Side Effects of Hyaluronidase / Hyalase
Side effects are uncommon, but may include:
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Allergic reaction:
This may be mild (local redness or swelling) or, rarely, severe (anaphylaxis). -
Excessive product dissolution:
Overcorrection may occur, reversing previous treatment effects. -
Infection:
A general risk whenever the skin is penetrated.
Your practitioner will discuss all potential risks and safety precautions before any procedure.
Common Treatment Areas
The most frequent areas where Hyalase / hyaluronidase may be used include:
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Under-eye region (tear troughs)
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Lips
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Cheeks
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Temples
Images of Typical Cases
Photographs below demonstrate common examples of aesthetic irregularities that may require review or management with Hyalase / hyaluronidase by a medical practitioner.





