Hyaluronidase | Hyalase

Hyaluronidase was used to dissolve prior treatments
Hyaluronidase was used to dissolve prior treatments

Hyaluronidase (Hyalase) Information – The Manse Clinic Sydney

This is a prescription-only product that may be used by a qualified medical practitioner in certain situations to address complications related to previous cosmetic procedures.


Situations Where Hyaluronidase / Hyalase May Be Considered

  • Lumps or bumps:
    Hyalase / hyaluronidase may be used by a doctor to help dissolve localised irregularities.

  • Unevenness of results:
    In some cases, Hyalase / hyaluronidase may be used to smooth the appearance of treated areas.

  • Infections:
    When infection is associated with a previous cosmetic procedure, Hyalase / hyaluronidase may be part of a management plan as determined by the treating doctor.

  • Blue appearance under the skin (Tyndall effect):
    This may improve following medical treatment with Hyalase / hyaluronidase.

  • Asymmetry:
    Hyalase / hyaluronidase may be used to reduce product volume in one area to improve balance.

  • Overtreatment:
    Where excessive product is present, Hyalase / hyaluronidase can assist in reducing the amount.

  • Vascular events:
    In rare cases where blood flow is compromised after a cosmetic procedure, Hyalase / hyaluronidase may be administered promptly by a doctor as part of emergency management to help restore circulation and reduce the risk of tissue injury.


Procedure for Hyaluronidase / Hyalase Treatment

  1. The patient will be assessed through history and examination, and treatment options will be discussed.

  2. Risks and potential side effects will be reviewed.

  3. Photos may be taken for documentation.

  4. If appropriate, a needle aspiration of the area may be performed instead of Hyalase / hyaluronidase use.

  5. If allergy is a concern, a test patch on the forearm may be performed prior to treatment.

  6. The skin will be cleaned before the procedure.

  7. Pressure will be applied to the treated area with sterile gauze afterward.

Patients may notice improvement within 1–2 days.
A review appointment is recommended at 1–4 weeks, once any swelling has subsided.


Risks and Side Effects of Hyaluronidase / Hyalase

Side effects are uncommon, but may include:

  • Allergic reaction:
    This may be mild (local redness or swelling) or, rarely, severe (anaphylaxis).

  • Excessive product dissolution:
    Overcorrection may occur, reversing previous treatment effects.

  • Infection:
    A general risk whenever the skin is penetrated.

Your practitioner will discuss all potential risks and safety precautions before any procedure.


Common Treatment Areas

The most frequent areas where Hyalase / hyaluronidase may be used include:

  • Under-eye region (tear troughs)

  • Lips

  • Cheeks

  • Temples


Images of Typical Cases

Photographs below demonstrate common examples of aesthetic irregularities that may require review or management with Hyalase / hyaluronidase by a medical practitioner.

NB Blue lump under right eye
NB Blue lump under right eye
Lump under eye 6 weeks after treatment, needs treatment with hyalase
Lump under eye 6 weeks after treatment, needs treatment with hyalase
Lump under the eye following a cosmetic treatment, may require assessment and management with Hyalase.jpg
Lump under the eye following a cosmetic treatment, may require assessment and management with Hyalase
Lump under right eye, 2 years after treatment of tear troughs, requires removal with hyalase
Lump under right eye, 2 years after treatment of tear troughs, requires removal with hyalase
Lumps and blue appearance (Tyndall effect)  For Hyalase hyaluronidase treatment
Lumps and blue appearance (Tyndall effect)  For Hyalase hyaluronidase treatment
Large lump in lip. Hyaluronidase / hyalase may be required to dissolve lump
Large lump in lip. Hyaluronidase / hyalase may be required to dissolve lump
THE MANSE